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臨床用藥論文步長(zhǎng)穩(wěn)心顆粒與倍他樂(lè)克聯(lián)用治療心律失常的臨床觀察
【摘要】 目的：觀察步長(zhǎng)穩(wěn)心顆粒與倍他樂(lè)克聯(lián)用治療心律失常的療效及耐受性。方法：將112 例心律失常的患者隨機(jī)分為兩組，治療組54 例采用步長(zhǎng)穩(wěn)心顆粒與較小劑量倍他樂(lè)克聯(lián)用治療；對(duì)照組58 例應(yīng)用較大劑量倍他樂(lè)克治療。觀察療效及耐受性。結(jié)果：治療1個(gè)月后治療組總有效率92.59 %，對(duì)照組總有效率81.82 %。兩組間差異有顯著性（P<0. 05 )。結(jié)論：步長(zhǎng)穩(wěn)心顆粒，較小劑量倍他樂(lè)克聯(lián)用治療心律失常有明顯療效，更易為病人耐受。
【關(guān)鍵詞】 心律失常 步長(zhǎng)穩(wěn)心顆粒 倍他樂(lè)克 Abstract ：Objective To investigate the effects and tolerance of wenxin keli withmetoprolol on arrhythmia. Methods 112 patients with arrhythmia were randomly dividedinto two groups. The treatment group(54 cases) treated with wenxin keli and lower dosemetoprolol, and the control group (48 cases) with higher dose metoprolol. Then observedthe clinical effects and tolerance. Results The total effects of treatment group were 92.59 %> those of the control group were 81.82 %, were significantly less than treatments（P<0.05)one month after treatment. Conclusion The wenxin keli with metoprolol iseffective on arrhythmia, and more easier to be tolerante by patients. Key words：Arrhythmia；Wenxin keli；Metoprolol
心律失常是臨床常見(jiàn)病癥之一，隨著我國(guó)人口老齡化，生活水平提高，冠心病，高血壓發(fā)病率增高，心律失常發(fā)病率亦增高。臨床常用倍他樂(lè)克等抗心律失常藥物治療，但由于倍他樂(lè)克在使用時(shí)有局限性，如致心率減慢、傳導(dǎo)阻滯、血壓降低、心力衰竭加重等，有急性心力衰竭，慢阻肺，高度房室傳導(dǎo)阻滯時(shí)禁忌使用，以及患者在認(rèn)識(shí)上的差異（西藥副作用大，中藥無(wú)毒副作用)而導(dǎo)致依從性差。對(duì)于農(nóng)村病人來(lái)說(shuō)，藥物最好是有效且副作用少。步長(zhǎng)穩(wěn)心顆粒是臨床上針對(duì)心律失常治療的一種中藥制劑，其與較小劑量倍他樂(lè)克聯(lián)用治療心律失常，與單獨(dú)應(yīng)用較大劑量倍他樂(lè)克治療比較，我們作臨床觀察分析現(xiàn)報(bào)告如下醫(yī)學(xué)全.在線jfsoft.net.cn。
