浙大醫(yī)學院病理學與病理生理學教授來茂德簡介

論文、教材和著作: SCI收錄論文51篇，最高影響因子8.894（2004年，是當時浙大醫(yī)學院所有研究工作在本土完成的最高影響因子期刊論文)。已在本學科頂尖期刊如《J Path》、《Clin Cancer Res》、《Am J Surg Path》、《Mod Path》、《Histopathology》、《Virchows Arch》等雜志上發(fā)表了論文。中文論文100余篇。主編衛(wèi)生部研究生規(guī)劃教材《醫(yī)學分子生物學》、副主編衛(wèi)生部七年制和八年制規(guī)劃教材《病理學》、幾乎參加所有病理學方面的主要著作和教材。主編研究專著《上皮內瘤變》、《惡性腫瘤組織病理學分級圖譜》、《 Intraepithelial Neoplasia》(該書全英文jfsoft.net.cn，所有400多張病理圖片都是中國人的，是國際上該領域的第一本專著，由中國高教出版社和世界著名圖書出版公司Springer聯(lián)合出版，目前在全世界銷售，在國際病理學界有很好影響)。

近年來代表性論文：
1.Lin J, Lai M, Huang Q, Ma Y, Cui J, Ruan W. Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. The Journal of pathology 2007;212: 83-90.
IF 5.423
2.Lu B, Xu J, Zhu Y, Zhang H, Lai M. Systemic analysis of the differential gene expression profile in a colonic adenoma-normal SSH library. Clinica chimica acta; international journal of clinical chemistry 2007;378: 42-7.
IF 2.601
3.MD L, Xujing. Ribosomal proteins and colorectal cancer. Current Genomics 2007;8: 43-9.
IF 0.573
4.Ruan W, Lai M. Actin, a reliable marker of internal control? Clinica chimica acta; international journal of clinical chemistry 2007;385: 1-5.
IF 2.601
5.Ruan W, Xu E, Xu F, et al. IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. Cancer biology & therapy 2007;6: 354-9. jfsoft.net.cn
IF 2.873
6.Wang Y, Ma Y, Lu B, Xu E, Huang Q, Lai M. Differential expression of mimecan and thioredoxin domain-containing protein 5 in colorectal adenoma and cancer: a proteomic study. Exp Biol Med (Maywood) 2007;232: 1152-9.
IF 1.979
7.Xu E, Xia X, Lu B, et al. Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese. Mol Carcinog 2007.
IF 3.194
8.Xu F, Wang F, Di M, et al. Classification based on the combination of molecular and pathologic predictors is superior to molecular classification on prognosis in colorectal carcinoma. Clin Cancer Res 2007;13: 5082-8.
IF 6.25
9.Ye F, Chen Y, Knosel T, et al. Decreased expression of insulin-like growth factor binding protein 7 in human colorectal carcinoma is related to DNA methylation. Journal of cancer research and clinical oncology 2007;133: 305-14.
IF 2.366
10.Zhu Y, Lai M, Yang H, et al. Genotypes, haplotypes and diplotypes of XPC and risk of bladder cancer. Carcinogenesis 2007;28: 698-703. jfsoft.net.cn
IF 5.406
11.Zhu YM, Huang Q, Lin J, Hu Y, Chen J, Lai MD. Expression of human DNA methyltransferase 1 in colorectal cancer tissues and their corresponding distant normal tissues. International journal of colorectal disease 2007;22: 661-6.
IF 1.918
12.Kang L, Lu B, Xu J, Hu H, Lai M. Downregulation of Kruppel-like factor 9 in human colorectal cancer. Pathol Int 2008;58: 334-8.
IF 1.371
13.Lu B, Fang Y, Xu J, et al. Analysis of SOX9 expression in colorectal cancer. Am J Clin Pathol 2008;130: 897-904.
IF 2.629
14.Lu B, Xu J, Chen J, Yu J, Xu E, Lai M. TaqMan low density array is roughly right for gene expression quantification in colorectal cancer. Clinica chimica acta; international journal of clinical chemistry 2008;389: 146-51.
IF 2.601

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